Dr. Oliver Sacks, a neurologist - Jarrett PorterMiriam H., a patient - Adrienne DanrichRose R., a patient - Joyce El-KhouryLeonard L., a patient - Andrew MorsteinIris L., Leonard’s mother - Katharine GoeldnerMr. Rodriguez, a nurse - César DelgadoDr. Podsnap, Beth Abraham Medical Director - Keith KleinRuth, a social worker - Erin Merceruio NelsonLily, Miriam’s daughter - Victoria DavisMiss Kohl, a speech therapist - Krista RiverLucy, a patient - Michelle TrainorFrank, a patient - Steven GoldsteinDr. Samuel Sacks, Dr. Oliver Sacks’s father - David SmallDr. Muriel Elsie Landau, Dr. Oliver Sacks’s mother - Stephanie KacoyanisRose’s fiancé - Sean MalkusLeonard, at 10 - Linus Schafer-GoulthorpeViolet, Miriam’s granddaughter - Madison SmithДирижер - Gil RoseРежиссер - James Robinson